Rated 4.9/5 by 4,281+ reviews

Meet TRIITMNT'S Protocol 45+

The first micro infusion system specifically designed for mature skin.

18 shield check

90-Day Money-Back Guarantee

"#1 SKINCARE TO GET RADIANT, HEALTHY SKIN AFTER 45"

3 Reasons Why Protocol 45+ Is The “One” For Mature Skin

1. It Gets Past The Barrier Creams Can't

Most skincare is simply rubbed onto the surface. Protocol 45+ creates thousands of tiny temporary pathways — giving your serum a better way in.

2. It's Built For 45+ Skin

Not 25-year-old skin. Not generic “anti-aging.” A concentrated 6-peptide formula built around wrinkles, crepiness, lost firmness and depleted-looking mature skin.

3. It Hits More Than One Sign Of Aging

Wrinkles. Texture. Firmness. Plumpness. Glow.

Better delivery. Better formula. Built for mature skin.

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Denise M., 62

Verified Buyer

“I got really self-conscious about the lines around my mouth because makeup kept settling into them and making them look worse. After using Protocol 45+, that whole area looks smoother, firmer and more hydrated. I’m wearing less makeup now because I don’t feel like I need to hide it anymore.”

Leslie B., 59

Verified Buyer

“My neck had started looking loose, crepey and much older than I felt. Creams never seemed to change it. After a few Protocol 45+ treatments, my neck looks smoother and noticeably firmer. I had started avoiding certain tops and photos, so seeing that area improve has been huge for me.”

Carla T., 57

Verified Buyer

“The heaviness in my lower face was aging me more than anything. My jawline looked softer and I was noticing jowls more every year. Protocol 45+ is the first thing that made a visible difference. My lower face looks firmer, my jawline looks better defined and I don’t look as dragged down anymore.”

Yvonne O., 61

Verified Buyer

“I’d done Botox before, but I got tired of the cost and constantly having to redo it. I wanted something I could maintain at home. Protocol 45+ genuinely surprised me. My skin looks smoother and firmer, especially around my mouth, and the result looks natural. I’m very happy I gave this a chance.”

Monica R., 56

Verified Buyer

“I have drawers full of expensive creams and serums that barely did anything beyond moisturizing my skin. Protocol 45+ felt completely different. After staying consistent with it, my skin looks smoother, firmer and much more alive. It’s one of the first at-home treatments I’ve bought that actually felt worth the money.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

Carla T., 57

Verified Buyer

“My forehead lines had gotten so deep that I noticed them every single time I looked in the mirror. After using Protocol 45+, my forehead looks smoother and my skin feels much more plump and fresh. The lines aren’t nearly as noticeable anymore. I still look like myself — just much less worn out.”

Patricia S., 65

Verified Buyer

“My skin had started looking thin and crepey, especially around my cheeks and lower face. That bothered me even more than the wrinkles. Protocol 45+ has made my skin look fuller, smoother and much healthier. It doesn’t have that same papery look anymore, and the overall firmness has improved noticeably.”

Elaine C., 58

Verified Buyer

“I’d gotten to the point where I hated seeing myself in photos because my skin always looked tired and older than I felt. Since using Protocol 45+, my skin looks smoother, firmer and much fresher in pictures. I don’t find myself avoiding the camera anymore, which has honestly meant a lot to me.”

Sandra K., 60

Verified Buyer

“The older I got, the worse foundation seemed to look because it settled into every line around my cheeks and mouth. Protocol 45+ has made my skin look smoother and much more hydrated, so makeup sits better and I need far less of it. My skin finally looks better instead of just more covered.”

Janice W., 63

Verified Buyer

“I was nervous to try Protocol 45+ because I assumed it would hurt, but it was much easier than I expected. After staying consistent, my skin looks firmer, smoother and more radiant, and some of the deeper lines look softer too. The treatment is simple enough that I actually look forward to using it.”

What you should expect from using TRIITMNT 45+

Here's what you can expect with bi-weekly use of 45+ protocol.

  • 18 shield check
    24 HOURS

    Skin Looks Plumper. Fast.

    Micro-infusion helps hydration get beyond the surface.

    Dry, tight, crepey-looking skin starts looking fuller.

    Skin looks smoother, fresher and noticeably more alive.

  • 18 shield check
    3 DAYS

    The Renewal Process Is Underway.

    Copper Tripeptide-1 and targeted peptides support mature-skin renewal.

    Crepey, fragile-looking skin starts feeling more resilient.

    Skin looks healthier instead of simply moisturized.

  • 18 shield check
    WEEK 1

    You Start Seeing It In The Mirror.

    Fine lines begin looking softer.

    Cheeks and eye area look plumper and less depleted.

    Texture looks smoother and that tired 45+ look starts fading.

  • 18 shield check
    MONTH 1

    This Is Where Creams Get Left Behind.

    Collagen-supporting peptides work on firmness and elasticity.

    Deeper-looking lines appear softer and less etched in.

    Jawline, cheeks and neck begin looking firmer and more defined.

  • 18 shield check
    MONTH 3

    Now The Difference Is Hard To Ignore.

    Wrinkles look smoother and crepey skin looks noticeably firmer.

    Skin looks fuller, tighter and more youthful.

    This is when the woman in the mirror starts looking like you again.

  • 18 shield check
    MONTH 6-12+

    Your Best 45+ Skin Becomes The New Normal.

    Firmness, plumpness and elasticity continue building with consistent use.

    Skin keeps looking smoother, stronger and healthier.

    The longer you follow Protocol 45+, the harder it becomes to remember why you settled for creams alone.

The Formula

The System

Built For 45+ Skin.

Designed To Get Past The Surface.

Protocol 45+ pairs a concentrated 6-peptide formula built for mature skin with virtually painless micro-infusion that gets past where creams stop.

Copper Tripeptide-1

Acetyl Hexapeptide-8

Multi-Peptide Firming Complex

Hyaluronic Acid + Hydrolyzed Collagen

Copper Tripeptide-1

Acetyl Hexapeptide-8

Multi-Peptide Firming Complex

Hyaluronic Acid + Hydrolyzed Collagen

2x 24K Gold-Plated Treatment Heads

2x 5ml Peptide Serum Vials

Twist. Stamp. Infuse.

EO Sterilized + Individually Sealed

2x 24K Gold-Plated Treatment Heads

2x 5ml Peptide Serum Vials

Twist. Stamp. Infuse.

EO Sterilized + Individually Sealed

Copper Tripeptide-1

Helps visibly firm, renew and revive tired 45+ skin.

Acetyl Hexapeptide-8

Supports firmer-looking skin and helps visibly improve signs of age-related skin decline.

Multi-Peptide Firming Complex

Supports firmer-looking skin and helps visibly improve signs of age-related skin decline.

Hyaluronic Acid + Hydrolyzed Collagen

Supports firmer-looking skin and helps visibly improve signs of age-related skin decline.

2x 24K Gold-Plated Treatment Heads

2x 5ml Peptide Serum Vials

Twist. Stamp. Infuse.

EO Sterilized + Individually Sealed

FAQs

What is Protocol 45+ and how does it work?

Protocol 45+ combines virtually painless micro-infusion with a concentrated 6-peptide serum built specifically for mature skin.

Ultra-fine treatment points create tiny temporary pathways through the skin’s surface barrier, helping the serum get beyond where ordinary creams stop.

Instead of simply moisturizing 45+ skin from the outside, Protocol 45+ targets the look of wrinkles, crepey texture, lost firmness, dryness and depleted-looking skin.

How quickly will I see results?

Many women notice smoother, plumper and more hydrated-looking skin after their first treatment.

The bigger changes build with consistency. Over the following treatments, look for softer-looking wrinkles, firmer skin and improved texture.

For deeper wrinkles and more advanced signs of aging, we recommend giving Protocol 45+ the full 90 days to judge your results.

Does it hurt?

Protocol 45+ is designed to be virtually painless.

You may feel a slight prickling or tingling sensation as the ultra-fine treatment points contact your skin, but most of the treatment should feel surprisingly comfortable.

Is Protocol 45+ safe to use at home?

Yes. Protocol 45+ is specifically designed for at-home use when used as directed.

Each 24K gold-plated treatment head is EO sterilized and individually sealed. Always follow the included treatment and aftercare instructions.

If you have an active or serious skin condition, speak with your healthcare professional before use.

Is it easy to use? Are there clear instructions?

Yes. Protocol 45+ is simple and straightforward to use, and one treatment takes just 5–10 minutes.

Every order comes with clear step-by-step instructions covering setup, application, treatment areas and aftercare.

Even if you’ve never used micro-infusion before, you’ll be guided through the entire process from start to finish.

Do I have to sign up for a subscription?

Yes. We believe Protocol 45+, alongside cleansing, hydration, sun protection and a consistent skincare routine, is one of the best ways to support visibly healthier-looking mature skin.

Consistent treatments are the best way to get the most out of Protocol 45+. By signing up for a subscription, you can easily build your 45+ skin protocol into your routine without worrying about reordering.

But we want you to feel good about trying it. That’s why you can use Protocol 45+ risk-free for 90 days. You can also reschedule or cancel your subscription anytime from your account.

How many treatment heads and serum vials are included?

Each Protocol 45+ box contains:

2x 24K Gold-Plated Micro-Infusion Heads

2x 5ml Peptide Serum Vials

That gives you 2 complete treatments, designed to be used approximately every 2 weeks.

Each sterile treatment head is intended for single use only.

Can I use it around my eyes, mouth and neck?

Yes. Protocol 45+ can be used across the face and neck where mature skin commonly shows wrinkles, crepiness and lost firmness.

Around delicate areas such as the eyes, use very gentle pressure and never stamp directly on the eyelids or waterline.

Follow the treatment-area guide included with your order.

What are the full serum ingredients?

Protocol 45+ features a 6-peptide complex, Sodium Hyaluronate and Hydrolyzed Collagen formulated around the visible concerns of mature skin.

Full ingredient list:

Water, Glycerin, Butylene Glycol, Copper Tripeptide-1, 1,2-Hexanediol, Hydroxyacetophenone, Mannitol, Carbomer, Arginine, Sodium Hyaluronate, Hydrolyzed Collagen, Acetyl Hexapeptide-8, Sodium Lactate, Polysorbate-20, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7.

What skincare can I use before and after treatment?

Start every treatment with completely clean, dry skin.

Afterwards, keep your routine simple and gentle. Hydrating skincare can be used as directed, but avoid retinoids, exfoliating acids and other strong actives for 24–48 hours while your skin recovers.

Avoid makeup immediately after treatment and follow the complete aftercare instructions included with your order.

Can I use Protocol 45+ if I’ve had Botox, fillers or other cosmetic treatments?

Yes, but give recently treated skin time to settle first.

As a general rule, wait at least 2 weeks after Botox, fillers or similar cosmetic injections before using Protocol 45+.

If your injector or healthcare provider recommends waiting longer, follow their guidance.

Is it suitable for all skin types and skin tones?

Protocol 45+ is designed to be suitable for a wide range of skin types and skin tones.

If your skin is particularly sensitive or reactive, start gently and carefully follow the treatment instructions.

If you have an active or serious skin condition, consult your healthcare professional before use.

Can Protocol 45+ help with deeper wrinkles and crepey skin?

Yes. Those are exactly the kinds of visible 45+ skin concerns Protocol 45+ was built to target.

Deeper wrinkles and crepey-looking skin generally take longer to improve than surface dryness or dullness, so consistency matters.

Give the protocol the full 90 days and look for progressively smoother, firmer and plumper-looking skin.

What if I don’t see the results I expected?

Then we take the risk, not you.

Give Protocol 45+ a fair try for up to 90 days. If you’re not happy with how your skin looks and feels, contact us within the guarantee period and we’ll refund your purchase under our 90-day money-back guarantee.

Give Us 90 Days To Change Your Skin Or Your Pay Nothing

Use Protocol 45+ consistently and give your skin the full 90-day protocol.

If you’re not happy with how your skin looks and feels, we’ll refund 100% of your purchase.

You try the protocol. We take the risk.

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